Bruno Mégarbane Selected Research

Tramadol (K315)

4/2022	[Severe hypoglycemia with cardiac arrest after massive tramadol ingestion - a case report].
3/2022	Marked and prolonged serotonin toxicity in a tramadol-poisoned patient with a pharmacokinetic study.
1/2022	Exposure to immediate-release tramadol in children 6 years and under - a nationwide French poison control center study.
1/2022	Intravenous Lipid Emulsion for treating Tramadol-Induced Seizures: Surprising but Worth Considering for Future Studies; a Letter to Editor.
1/2022	Massive tramadol ingestion resulting in fatal brain injury - a pharmacokinetic study with discussion on the involved mechanisms of toxicity.
8/2020	Trends in severe opioid-related poisonings and fatalities reported to the Paris poison control center - a 10-year retrospective observational study.
1/2019	Seizures induced by tramadol overdose: what is the respective contribution of tramadol and each of its metabolites?
11/2018	Tramadol: Distinguishing the Pathophysiology of Serotonin Syndrome and Seizures.
1/2018	Is naloxone the best antidote to reverse tramadol-induced neuro-respiratory toxicity in overdose? An experimental investigation in the rat.
1/2017	Bifunctional peptide-based opioid agonist/nociceptin antagonist ligand for dual treatment of nociceptive and neuropathic pain.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Bruno Mégarbane Research Topics

Disease

75	Poisoning 04/2022 - 01/2002
31	COVID-19 04/2022 - 01/2020
21	Respiratory Insufficiency (Respiratory Failure) 01/2022 - 01/2006
15	Heart Arrest (Cardiac Arrest) 04/2022 - 10/2004
14	Seizures (Absence Seizure) 01/2022 - 01/2002
12	Infections 06/2021 - 05/2004
11	Critical Illness (Critically Ill) 12/2021 - 04/2010
10	Coma (Comas) 01/2022 - 01/2002
8	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 04/2022 - 06/2011
7	Hypoxia (Hypoxemia) 01/2022 - 05/2006
6	Sepsis (Septicemia) 01/2021 - 05/2004
5	Pneumonia (Pneumonitis) 04/2022 - 12/2013
5	Hypotension (Low Blood Pressure) 01/2022 - 01/2004
5	Serotonin Syndrome (Syndrome, Serotonin) 05/2021 - 12/2012
5	Shock 01/2021 - 06/2011
4	Cardiogenic Shock 06/2022 - 01/2013
4	Catheter-Related Infections 01/2022 - 08/2010
4	Brain Diseases (Brain Disorder) 12/2021 - 06/2007
4	Hemorrhage 09/2021 - 01/2010
4	Wounds and Injuries (Trauma) 01/2020 - 01/2010
4	Pain (Aches) 01/2020 - 01/2010
4	Renal Insufficiency (Renal Failure) 01/2017 - 02/2005
4	Hypertension (High Blood Pressure) 03/2016 - 08/2010
4	Heroin Dependence (Heroin Abuse) 09/2012 - 01/2006
3	Hypoglycemia (Reactive Hypoglycemia) 04/2022 - 12/2017
3	Respiratory Tract Infections (Respiratory Tract Infection) 04/2022 - 01/2018
3	Paralysis (Palsy) 03/2022 - 01/2016
3	Status Epilepticus (Complex Partial Status Epilepticus) 01/2022 - 04/2015
3	Obesity 01/2022 - 01/2016
3	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 09/2020
3	Inflammation (Inflammations) 12/2020 - 01/2020
3	Heart Failure 04/2019 - 09/2006
3	Edema (Dropsy) 01/2019 - 01/2016
3	Bradycardia 03/2017 - 07/2012
3	Lactic Acidosis 01/2011 - 09/2002
2	Cardiotoxicity 09/2022 - 01/2007
2	Virus Diseases (Viral Diseases) 04/2022 - 01/2021
2	Superinfection 04/2022 - 12/2020
2	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2022 - 12/2013
2	Thrombosis (Thrombus) 09/2021 - 01/2020

Drug/Important Bio-Agent (IBA)

15	Pharmaceutical PreparationsIBA 02/2022 - 04/2003
13	Buprenorphine (Subutex)FDA LinkGeneric 01/2022 - 01/2006
12	Opioid Analgesics (Opioids)IBA 01/2022 - 01/2006
11	Tramadol (K315)FDA LinkGeneric 04/2022 - 11/2016
11	LithiumIBA 01/2021 - 09/2013
7	Lactic Acid (Lactate)FDA LinkGeneric 11/2020 - 09/2002
6	Dexamethasone (Maxidex)FDA LinkGeneric 04/2022 - 12/2006
6	Naloxone (Narcan)FDA LinkGeneric 11/2020 - 06/2010
6	Fomepizole (Antizol)FDA LinkGeneric 01/2020 - 01/2002
6	BenzodiazepinesIBA 11/2016 - 10/2004
5	Diazepam (Valium)FDA LinkGeneric 01/2022 - 12/2012
5	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2021 - 01/2019
5	Ethanol (Ethyl Alcohol)IBA 11/2020 - 10/2004
5	Methanol (Carbinol)IBA 08/2020 - 02/2005
5	AntidotesIBA 08/2020 - 01/2018
5	Morphine (MS Contin)FDA LinkGeneric 08/2020 - 12/2009
5	Methadone (Dolophine)FDA LinkGeneric 08/2013 - 01/2007
5	Cyanides (Isocyanides)IBA 01/2011 - 09/2002
4	Serotonin (5 Hydroxytryptamine)IBA 03/2022 - 12/2012
4	Acetaminophen (Paracetamol)FDA LinkGeneric 12/2021 - 10/2008
4	Chloroquine (Aralen)FDA LinkGeneric 01/2021 - 07/2005
4	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 01/2021 - 07/2005
4	Ethylene Glycol (Monoethylene Glycol)IBA 01/2020 - 02/2005
4	Baclofen FDA LinkGeneric 01/2018 - 11/2015
4	Insulin (Novolin)FDA Link 12/2017 - 01/2004
3	Oxygen (Dioxygen)IBA 04/2022 - 01/2019
3	ParaquatIBA 04/2022 - 06/2009
3	Cyproheptadine (Periactin)FDA Link 03/2022 - 12/2012
3	Illicit Drugs (Recreational Drugs)IBA 02/2022 - 04/2008
3	CatecholaminesIBA 02/2022 - 01/2004
3	Intravenous Fat EmulsionsIBA 01/2022 - 07/2015
3	Biological ProductsIBA 01/2022 - 04/2003
3	Psychotropic Drugs (Psychoactive Drugs)IBA 01/2022 - 01/2006
3	Colchicine FDA LinkGeneric 12/2021 - 01/2021
3	Peptides (Polypeptides)IBA 10/2021 - 01/2017
3	BradykininIBA 10/2021 - 01/2021
3	Biomarkers (Surrogate Marker)IBA 09/2021 - 03/2009
3	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2021 - 01/2004
3	EnzymesIBA 01/2021 - 01/2020
3	Anti-Bacterial Agents (Antibiotics)IBA 12/2020 - 08/2010
3	Epinephrine (Adrenaline)FDA LinkGeneric 03/2017 - 01/2004
3	Heroin (Diamorphine)IBA 12/2013 - 01/2007
3	norbuprenorphineIBA 03/2013 - 05/2006
3	CreatinineIBA 01/2013 - 01/2010
2	AutoantibodiesIBA 01/2022 - 01/2022
2	VenomsIBA 09/2021 - 06/2018
2	AngiotensinsIBA 06/2021 - 01/2021
2	Kallikreins (Kallikrein)IBA 06/2021 - 01/2021
2	Furosemide (Lasix)FDA LinkGeneric 01/2021 - 01/2021

Therapy/Procedure

15	Extracorporeal Membrane Oxygenation 04/2022 - 09/2006
15	Therapeutics 11/2021 - 01/2002
12	Artificial Respiration (Mechanical Ventilation) 04/2022 - 08/2010
8	Catheters 01/2022 - 05/2008
6	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2022 - 04/2010
6	Critical Care (Surgical Intensive Care) 01/2022 - 05/2004
5	Renal Dialysis (Hemodialysis) 01/2016 - 02/2005
4	Cardiopulmonary Resuscitation (CPR) 03/2016 - 05/2007
3	Mechanical Ventilators (Ventilator) 04/2022 - 01/2018
3	Central Venous Catheters 01/2022 - 09/2016
3	Duration of Therapy 06/2019 - 01/2017